SubtiBank SubtiBank
pksN [2018-02-13T14:27:54.000Z]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

pksN [2018-02-13T14:27:54.000Z]

polyketide synthase of type I
Locus
BSU17210
Isoelectric point
5.47
Molecular weight
609.00 kDa
Protein length
5488 aa Sequence Blast
Gene length
16464 bp Sequence Blast
Function
polyketide synthesis
Product
polyketide synthase of type I
Essential
no
Synonyms
pksP

Genomic Context

      
Loading

Categories containing this gene/protein

Gene

Coordinates
1,834,409 → 1,850,875

The protein

Paralogous protein(s)

  • shares highly conserved domains of more than 1,000 amino acids with: DhbF, PksJ, PksN, PpsA, PpsB, PpsC, PpsD, PpsE, SrfAA, SrfAB, SrfAC
  • Expression and Regulation

    Operons

    Description

    Regulatory mechanism

  • AbrB: repression, PubMed, in AbrB regulon
  • CodY: activation, PubMed, in CodY regulon
  • Regulation

  • expressed during the transition from growth to stationary phase (AbrB, CodY) PubMed
  • Additional information

  • this is a very large operon comprising about 75 kb
  • view in new tab

    Biological materials

    Mutant

  • BKE17210 (ΔpksN::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGCCTTTAAGATGTTCTT, downstream forward: _UP4_CTGTTATAGGAGGGGAAACG
  • BKK17210 (ΔpksN::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGCCTTTAAGATGTTCTT, downstream forward: _UP4_CTGTTATAGGAGGGGAAACG
  • References

    Loading